Clinicopathological findings, treatment, and outcome in 60 cats with gastrointestinal eosinophilic sclerosing fibroplasia.
J Vet Intern Med
; 38(2): 1005-1012, 2024.
Article
in En
| MEDLINE
| ID: mdl-38205893
ABSTRACT
BACKGROUND:
Gastrointestinal eosinophilic sclerosing fibroplasia (GESF) in cats presents as mass(es) associated with the gastrointestinal tract, mesentery, and abdominal lymph nodes. HYPOTHESIS/OBJECTIVES:
To report the clinicopathological findings, treatment, and outcome of cats with GESF. ANIMALS Sixty client-owned cats diagnosed with GESF.METHODS:
Retrospective review of medical records of cats with histopathologically confirmed GESF.RESULTS:
The median age was 5.4 years (interquartile range [IQR], 3.3-8.9.); 30% were Domestic Shorthairs and 12% were Domestic Longhair cats, with the most prevalent pedigree breeds being Ragdolls (25%), Exotic Shorthair (10%) and Persian (8%) cats. The median duration of clinical signs was 90 days (IQR, 17.5-247.0); the most common clinical signs were weight loss (60%), hyporexia/anorexia (55%), chronic vomiting (37%), lethargy (35%) and chronic diarrhea (27%). Masses were located in the small intestine (32%), stomach (27%), ileocolic junction (15%), colon (10%), lymph node (8%) and mesentery (8%) and 15% of cats had >1 mass. Eosinophilia was present in 50% and hypoalbuminemia in 28% of cats. The mass was removed surgically in 37% of cases. Most cats (98%) were treated with corticosteroids. Survival was not statistically different between cats treated with surgical resection and cats treated with medical therapy alone, 88% of the cats were still alive at the time of writing. CONCLUSIONS AND CLINICAL IMPORTANCE GESF is an important differential diagnosis for abdominal masses in cats, and has a much better prognosis than previously reported.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cat Diseases
/
Enteritis
/
Eosinophilia
/
Gastritis
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
J Vet Intern Med
Journal subject:
MEDICINA INTERNA
/
MEDICINA VETERINARIA
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: