Patterns of antibiotic administration in Chinese neonates: results from a multi-center, point prevalence survey.
BMC Infect Dis
; 24(1): 186, 2024 Feb 12.
Article
in En
| MEDLINE
| ID: mdl-38347526
ABSTRACT
OBJECTIVES:
In this study, we describe the patterns of antibiotic prescription for neonates based on World Health Organization's (WHO) Essential Medicines List Access, Watch, and Reserve (AWaRe), and the Management of Antibiotic Classification (MAC) Guidelines in China.METHODS:
One-day point-prevalence surveys (PPS) on antimicrobial prescriptions were conducted on behalf of hospitalized neonates in China from September 1 and November 30, annually from 2017 to 2019.RESULTS:
Data was collected for a total of 2674 neonatal patients from 15 hospitals in 9 provinces across China of which 1520 were newborns who received at least one antibiotic agent. A total of 1943 antibiotic prescriptions were included in the analysis. The most commonly prescribed antibiotic was meropenem (11.8%). The most common reason for prescribing antibiotic to neonates was pneumonia (44.2%). There were 419 (21.6%), 1343 (69.1%) and 6 (0.3%) antibiotic prescriptions in the Access, Watch and Reserve groups, respectively. According to MAC Guidelines in China, there were 1090 (56.1%) antibiotic agents in the Restricted and 414 (21.3%) in the Special group.CONCLUSION:
Broad-spectrum antibiotics included in the Watch and Special groups were likely to be overused in Chinese neonates.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Drug Prescriptions
/
Anti-Bacterial Agents
Type of study:
Clinical_trials
/
Prevalence_studies
/
Qualitative_research
/
Risk_factors_studies
Limits:
Humans
/
Newborn
Country/Region as subject:
Asia
Language:
En
Journal:
BMC Infect Dis
Journal subject:
DOENCAS TRANSMISSIVEIS
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: