Is allergen immunotherapy a model of personalized treatment in pediatric respiratory allergy?
Curr Opin Allergy Clin Immunol
; 24(2): 88-93, 2024 Apr 01.
Article
in En
| MEDLINE
| ID: mdl-38359080
ABSTRACT
PURPOSE OF REVIEW To review recent evidence on allergen immunotherapy (AIT) as a model of personalized medicine in the treatment of children and adolescents with respiratory allergies. RECENT FINDINGS:
Meta-analysis and systematic review studies continue to point out that AIT is an effective treatment for children with respiratory allergies. Molecular allergy allows the understanding of patient sensitization profiles that frequently change the prescription of AIT. There is still a lack of evidence showing that this personalized prescription of AIT is associated with better clinical outcomes. The nasal allergen challenge has extended the indications of AIT for a new group of subjects with local allergic rhinitis. Patient selection of allergens involved in the increasingly personalized composition of extracts to be used in AIT increasingly characterizes it as personalized medicine.SUMMARY:
Despite the numerous studies carried out to identify the best biomarker to evaluate the response to AIT, there is still much disagreement, and clinical assessment (symptoms, quality of life, among others) continues to be the best way to evaluate the therapeutic success of AIT.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Allergens
/
Desensitization, Immunologic
/
Precision Medicine
Type of study:
Prognostic_studies
Aspects:
Patient_preference
Limits:
Adolescent
/
Child
/
Humans
Language:
En
Journal:
Curr Opin Allergy Clin Immunol
Journal subject:
ALERGIA E IMUNOLOGIA
Year:
2024
Document type:
Article