Association of dietary inflammatory index and the SARS-CoV-2 infection incidence, severity and mortality of COVID-19: a systematic review and dose-response meta-analysis.
Nutr J
; 23(1): 21, 2024 Feb 20.
Article
in En
| MEDLINE
| ID: mdl-38373980
ABSTRACT
BACKGROUND:
Several studies have reported the association between dietary inflammatory index (DII) and the SARS-CoV-2 infection risk, severity or mortality of COVID-19, however, the outcomes remain controversial.OBJECTIVE:
We sought to examine whether a dose-response association of DII and SARS-CoV-2 infection exists.DESIGN:
A dose-response meta-analysis was performed to investigate the association of DII and SARS-CoV-2 infection. We conducted a systematic search of PubMed, Embase and Web of Science up to March 15th, 2023. The odds ratios (OR) of DII and COVID-19 risk and severity were computed.RESULTS:
Totally, 5 studies were included (1 from UK and 4 from Iran), consisting of 197,929 participants with 12,081 COVID-19 cases. Although there was heterogeneity among studies, the results indicated that higher DII was independently related to higher SARS-CoV-2 infection incidence (OR = 1.57, 95% CI 1.14, 2.17) and COVID-19 severity (OR = 1.11, 95% CI 1.07, 1.15) but not COVID-19 mortality (risk ratio = 1.13, 95% CI 1.00, 1.27). The incidence of SARS-CoV-2 infection increased by 31% for each 1-point increase in the E-DII (OR = 1.31, 95% CI 1.20, 1.43).CONCLUSIONS:
This meta-analysis suggests that an elevated DII score is associated with increased SARS-CoV-2 infectious risk and severity of COVID-19. There were not enough studies on COVID-19 mortality. Further large prospective studies in different countries are warranted to validate our results.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Severity of Illness Index
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Diet
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SARS-CoV-2
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COVID-19
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Inflammation
Limits:
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Nutr J
/
Nutr. j. (Online)
/
Nutrition journal (Online)
Journal subject:
CIENCIAS DA NUTRICAO
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: