Revisiting the determinants of malaria transmission.
Trends Parasitol
; 40(4): 302-312, 2024 Apr.
Article
in En
| MEDLINE
| ID: mdl-38443304
ABSTRACT
Malaria parasites have coevolved with humans over thousands of years, mirroring their migration out of Africa. They persist to this day, despite continuous elimination efforts worldwide. These parasites can adapt to changing environments during infection of human and mosquito, and when expanding the geographical range by switching vector species. Recent studies in the human malaria parasite, Plasmodium falciparum, identified determinants governing the plasticity of sexual conversion rates, sex ratio, and vector competence. Here we summarize the latest literature revealing environmental, epigenetic, and genetic determinants of malaria transmission.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Malaria, Falciparum
/
Malaria
/
Culicidae
Limits:
Animals
/
Humans
Language:
En
Journal:
Trends Parasitol
Journal subject:
PARASITOLOGIA
Year:
2024
Document type:
Article
Affiliation country: