Physical activity-related individual differences in functional human connectome are linked to fluid intelligence in older adults.
Neurobiol Aging
; 137: 94-104, 2024 May.
Article
in En
| MEDLINE
| ID: mdl-38460470
ABSTRACT
The study examined resting state functional connectivity (rs-FC) associated with moderate-to-vigorous physical activity (MV-PA), sedentary time (ST), TV viewing, computer use, and their relationship to cognitive performance in older adults. We used pre-intervention data from 119 participants from the Fit & Active Seniors trial. Multivariate pattern analysis revealed two seeds associated with MV-PA right superior frontal gyrus (SFG; spanning frontoparietal [FPN] and ventral attention networks [VAN]) and right precentral (PrG) and postcentral gyri (PoG) of the somatosensory network (SN). A positive correlation between the right SFG seed and a cluster spanning default mode (DMN), dorsal attention (DAN), FPN, and visual networks (VIS) was linked to higher fluid intelligence, as was FC between the right PrG/PoG seed and a cluster in VIS. No significant rs-FC patterns associated with ST, TV viewing, or computer use were found. Our findings suggest that greater functional integration within networks implementing top-down control and within those supporting visuospatial abilities, paired with segregation between networks critical and those not critical to top-down control, may help promote cognitive reserve in more physically active seniors.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Connectome
Limits:
Aged
/
Humans
Language:
En
Journal:
Neurobiol Aging
Year:
2024
Document type:
Article