[Pulmonary lipofibroblasts in adults and alveolar regeneration in emphysema]. / Lipofibroblastes pulmonaires chez l'adulte et régénération alvéolaire au cours de l'emphysème.
Rev Mal Respir
; 41(4): 299-302, 2024 Apr.
Article
in Fr
| MEDLINE
| ID: mdl-38461092
ABSTRACT
Lipofibroblasts form a sub-population of fibroblasts located in the mesenchymal alveolar stem cell niche. They show close proximity with alveolar epithelial type 2 cells and play a key role in alveolar development and lung homeostasis. Their role in various diseases such as acute respiratory distress syndrome, pulmonary fibrosis and emphysema is progressively better understood. Through the activation of signaling pathways such as PPARg lipofibroblasts may help to induce endogenous alveolar regeneration.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pulmonary Emphysema
/
Emphysema
Limits:
Adult
/
Humans
Language:
Fr
Journal:
Rev Mal Respir
Year:
2024
Document type:
Article
Country of publication: