Langerhans cell histiocytosis in children with refractory diarrhoea and hypoalbuminaemia as the initial presentation: two case reports and a literature review.
BMC Pediatr
; 24(1): 203, 2024 Mar 22.
Article
in En
| MEDLINE
| ID: mdl-38519924
ABSTRACT
Langerhans cell histiocytosis (LCH) involving the gastrointestinal tract is a rare condition for which clinical experience is limited. We describe the cases of two patients who initially presented with chronic diarrhoea, hypoproteinaemia, and intermittent fever. These findings suggest that in cases of refractory diarrhoea accompanied by recurrent hypoalbuminaemia, especially with abdominal rash, LCH should be considered. Gastrointestinal endoscopy, biopsy, and imaging studies are essential for obtaining a definitive diagnosis. This approach might be helpful for the early recognition of gastrointestinal tract involvement in LCH.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Histiocytosis, Langerhans-Cell
/
Hypoalbuminemia
Limits:
Child
/
Humans
Language:
En
Journal:
BMC Pediatr
/
BMC pediatr. (Online)
/
BMC pediatrics (Online)
Journal subject:
PEDIATRIA
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: