[Research progress on pathogenesis of malignant mesothelioma].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
; 42(3): 232-240, 2024 Mar 20.
Article
in Zh
| MEDLINE
| ID: mdl-38538248
ABSTRACT
The occurrence of malignant mesothelioma is related to exposure of asbestos. And many researchers have conducted in-depth analysis of the molecular changes of mesothelioma, showed that its molecular characteristics were chromosome changes, including chromosome rearrangement, gene mutation and gene deletion. Recent studies have strengthened our understanding of molecular characterization of mesothelioma, such as targeted mutations of tumor suppressor genes, differential gene expression, changes of miRNA and signal pathways. It is of great significance for the early diagnosis, clinical treatment and prognosis of malignant mesothelioma to explore the pathogenesis and development of malignant mesothelioma. This article reviews the research progress on the pathogenesis and carcinogenesis-related molecules of malignant mesothelioma.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pleural Neoplasms
/
Asbestos
/
Mesothelioma, Malignant
/
Lung Neoplasms
/
Mesothelioma
Limits:
Humans
Language:
Zh
Journal:
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
Journal subject:
MEDICINA OCUPACIONAL
Year:
2024
Document type:
Article
Affiliation country: