Association between habitual betel quid chewing and risk of adverse cardiovascular outcomes: A systematic review.
Trop Med Int Health
; 29(6): 447-453, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38556799
ABSTRACT
INTRODUCTION:
Habitual betel quid chewing, a tobacco product, is a leading cause of oral cancer in Asia-Pacific countries where this practice is most prevalent. However, it is not well understood whether betel quid chewing is also a cause of adverse cardiovascular outcomes. To address this gap, we conducted a systematic literature review of peer-reviewed published studies evaluating the association between habitual betel quid use on the risk of adverse cardiovascular outcomes.METHODS:
We searched PubMed for studies assessing the correlation between betel quid chewing and cardiovascular health. We included studies if (i) they included human subjects; (ii) were peer-reviewed articles in indexed journals; and (iii) were in English. We extracted data from eligible studies and stratified them by geographical location, study designs and cardiovascular outcomes. Finally, we did a narrative synthesis of the data to identify adverse cardiovascular outcomes associated with chronic betel quid use.FINDINGS:
We reviewed data from 19 studies that met the inclusion criteria. Habitual betel quid chewing was associated with hypertension, atherosclerosis, inflammation and ischaemic heart disease. In addition, betel quid use was a risk factor for arrhythmias. Interestingly, betel quid use was an independent risk factor for cardiovascular disease in women. Long-term betel quid consumption was associated with higher risks for all-cause mortality and increased overall cardiovascular risk.CONCLUSIONS:
Habitual betel quid chewing is an important cardiovascular risk factor in populations where the practice is prevalent.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Areca
/
Cardiovascular Diseases
Limits:
Female
/
Humans
/
Male
Language:
En
Journal:
Trop Med Int Health
Journal subject:
MEDICINA TROPICAL
/
SAUDE PUBLICA
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: