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A phase I open-label, dose-escalation study of NUC-3373, a targeted thymidylate synthase inhibitor, in patients with advanced cancer (NuTide:301).
Spiliopoulou, Pavlina; Kazmi, Farasat; Aroldi, Francesca; Holmes, Thomas; Thompson, David; Griffiths, Lucinda; Qi, Cathy; Parkes, Matthew; Lord, Simon; Veal, Gareth J; Harrison, David J; Coyle, Vicky M; Graham, Jill; Jeffry Evans, Thomas R; Blagden, Sarah P.
Affiliation
  • Spiliopoulou P; School of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Kazmi F; Beatson West of Scotland Cancer Centre, Glasgow, UK.
  • Aroldi F; Early Phase Clinical Trials Unit, Churchill Hospital, Oxford University Hospitals, Oxford, UK.
  • Holmes T; Early Phase Clinical Trials Unit, Churchill Hospital, Oxford University Hospitals, Oxford, UK.
  • Thompson D; Department of Oncology, Oncology Clinical Trials Office, University of Oxford, Oxford, UK.
  • Griffiths L; Department of Oncology, Oncology Clinical Trials Office, University of Oxford, Oxford, UK.
  • Qi C; Department of Oncology, Oncology Clinical Trials Office, University of Oxford, Oxford, UK.
  • Parkes M; Centre for Statistics in Medicine and Oxford Clinical Trials Research Unit (OCTRU), Oxford, UK.
  • Lord S; Centre for Statistics in Medicine and Oxford Clinical Trials Research Unit (OCTRU), Oxford, UK.
  • Veal GJ; Early Phase Clinical Trials Unit, Churchill Hospital, Oxford University Hospitals, Oxford, UK.
  • Harrison DJ; Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK.
  • Coyle VM; School of Medicine, University of St Andrews, St Andrews, UK.
  • Graham J; NuCana plc, 3 Lochside Way, Edinburgh, UK.
  • Jeffry Evans TR; Patrick G. Johnston Centre for Cancer Research, Queens University Belfast, Belfast, UK.
  • Blagden SP; Beatson West of Scotland Cancer Centre, Glasgow, UK.
J Exp Clin Cancer Res ; 43(1): 100, 2024 Apr 02.
Article in En | MEDLINE | ID: mdl-38566164

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Floxuridine / Neoplasms Limits: Humans Language: En Journal: J Exp Clin Cancer Res Year: 2024 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Floxuridine / Neoplasms Limits: Humans Language: En Journal: J Exp Clin Cancer Res Year: 2024 Document type: Article Affiliation country: Country of publication: