Clinical Evaluation of the Adult with Eosinophilic Esophagitis.
Immunol Allergy Clin North Am
; 44(2): 185-196, 2024 May.
Article
in En
| MEDLINE
| ID: mdl-38575217
ABSTRACT
Adult patients with eosinophilic esophagitis (EoE) typically present with a history of dysphagia for solids, sometimes with additional reflux-like pain and a history of prior food impactions. In contrast to these alarming symptoms, the general appearance and physical examination of adult patients with EoE is in line with apparently healthy individuals. Therefore, the diagnosis is based on a history of solid-food dysphagia and eosinophilic tissue infiltration. Importantly, the increasing prevalence of EoE variants, that is, typical EoE symptoms in the absence of a relevant eosinophilia, and several studies with eosinophil-targeting drugs, call the pathogenic role of eosinophils into question.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Deglutition Disorders
/
Enteritis
/
Eosinophilia
/
Eosinophilic Esophagitis
/
Gastritis
Limits:
Adult
/
Humans
Language:
En
Journal:
Immunol Allergy Clin North Am
Journal subject:
ALERGIA E IMUNOLOGIA
Year:
2024
Document type:
Article
Country of publication: