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Treatment Response Biomarkers: Working Toward Personalized Radiotherapy for Lung Cancer.
Horne, Ashley; Harada, Ken; Brown, Katherine D; Chua, Kevin Lee Min; McDonald, Fiona; Price, Gareth; Putora, Paul Martin; Rothwell, Dominic G; Faivre-Finn, Corinne.
Affiliation
  • Horne A; Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom; Department of Radiation Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom. Electronic address: ashley.horne3@nhs.net.
  • Harada K; Department of Radiation Oncology, Showa University Northern Yokohama Hospital, Tsuzuki-ku, Yokohama, Kanagawa, Japan.
  • Brown KD; Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom; Department of Research and Innovation, The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom.
  • Chua KLM; Division of Radiation Oncology, National Cancer Centre Singapore, Singapore.
  • McDonald F; Royal Marsden Hospital, London, UK.
  • Price G; Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom.
  • Putora PM; Department of Radiation Oncology, Kantonsspital St. Gallen, St. Gallen, Switzerland; Department of Radiation Oncology, Inselspital, University of Bern, Bern, Switzerland.
  • Rothwell DG; CR-UK National Biomarker Centre, University of Manchester, Manchester, United Kingdom.
  • Faivre-Finn C; Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom; Department of Radiation Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom.
J Thorac Oncol ; 19(8): 1164-1185, 2024 Aug.
Article in En | MEDLINE | ID: mdl-38615939
ABSTRACT
Owing to major advances in the field of radiation oncology, patients with lung cancer can now receive technically individualized radiotherapy treatments. Nevertheless, in the era of precision oncology, radiotherapy-based treatment selection needs to be improved as many patients do not benefit or are not offered optimum therapies. Cost-effective robust biomarkers can address this knowledge gap and lead to individuals being offered more bespoke treatments leading to improved outcome. This narrative review discusses some of the current achievements and challenges in the realization of personalized radiotherapy delivery in patients with lung cancer.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precision Medicine / Lung Neoplasms Limits: Humans Language: En Journal: J Thorac Oncol / J. thorac. oncol / Journal of thoracic oncology Year: 2024 Document type: Article Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precision Medicine / Lung Neoplasms Limits: Humans Language: En Journal: J Thorac Oncol / J. thorac. oncol / Journal of thoracic oncology Year: 2024 Document type: Article Country of publication: