Patient-Derived Xenograft Models for Ovarian Cancer.
Methods Mol Biol
; 2806: 187-196, 2024.
Article
in En
| MEDLINE
| ID: mdl-38676803
ABSTRACT
Patient-derived xenograft (PDX) models play a crucial role for in vivo research. They maintain the original molecular characteristics of the human tumor and provide a more accurate tumor microenvironment, which cannot be replicated by in vitro models. This chapter describes four different transplantation methods, namely, intra-bursal, intrarenal capsule, intraperitoneal, and subcutaneous, to develop PDX models for ovarian cancer research.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ovarian Neoplasms
/
Xenograft Model Antitumor Assays
/
Disease Models, Animal
Limits:
Animals
/
Female
/
Humans
Language:
En
Journal:
Methods Mol Biol
Journal subject:
BIOLOGIA MOLECULAR
Year:
2024
Document type:
Article
Affiliation country: