[Research progress on ferroptosis in tumor immunity].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
; 40(4): 362-366, 2024 Apr.
Article
in Zh
| MEDLINE
| ID: mdl-38710519
ABSTRACT
Ferroptosis is a novel form of cell death that is induced by excessive accumulation of ferrous ions and lipid peroxides. It triggers the release of damage-associated molecular patterns through autophagy-dependent mechanisms, serving as an adjunct to immunogenic cell death and activating both adaptive and innate immunity. In the tumor microenvironment, the regulation and influence of tumor cells and immune cells undergoing ferroptosis are regulated by various factors, which plays a crucial role in tumor development, treatment, and prognosis. This article provides an overview of the biological effects of ferroptosis on immune cells such as T cells, macrophages, neutrophils and B cells and tumor cells in the tumor microenvironment.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tumor Microenvironment
/
Ferroptosis
/
Neoplasms
Limits:
Animals
/
Humans
Language:
Zh
Journal:
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
Journal subject:
ALERGIA E IMUNOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: