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A novel dual near-infrared fluorescent probe for bioimaging and visualization of viscosity in acute alcoholic liver injury.
Wang, Ruonan; Zhou, Xucong; Li, Bingxue; Ding, Ru; Han, Jingqian; Wang, Ying; Meng, Aixia; Zhou, Jin.
Affiliation
  • Wang R; School of Pharmacy, School of Nursing, School of Basic Medical Sciences, Shandong Second Medical University, Weifang 261053, China. zhoujin@sdsmu.edu.cn.
  • Zhou X; School of Pharmacy, School of Nursing, School of Basic Medical Sciences, Shandong Second Medical University, Weifang 261053, China. zhoujin@sdsmu.edu.cn.
  • Li B; School of Pharmacy, School of Nursing, School of Basic Medical Sciences, Shandong Second Medical University, Weifang 261053, China. zhoujin@sdsmu.edu.cn.
  • Ding R; School of Pharmacy, School of Nursing, School of Basic Medical Sciences, Shandong Second Medical University, Weifang 261053, China. zhoujin@sdsmu.edu.cn.
  • Han J; School of Pharmacy, School of Nursing, School of Basic Medical Sciences, Shandong Second Medical University, Weifang 261053, China. zhoujin@sdsmu.edu.cn.
  • Wang Y; Faculty of Education, Qufu Normal University, Qufu 273165, China.
  • Meng A; School of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao 266071, China. wangying@uor.edu.cn.
  • Zhou J; School of Pharmacy, School of Nursing, School of Basic Medical Sciences, Shandong Second Medical University, Weifang 261053, China. zhoujin@sdsmu.edu.cn.
Chem Commun (Camb) ; 60(45): 5804-5807, 2024 May 30.
Article in En | MEDLINE | ID: mdl-38712712
ABSTRACT
A dual NIR fluorescent probe Cy-ND is developed for viscosity sensing with λex/em = 766/806 nm, making it apt for biological analysis, whose response is validated through DFT and TDDFT computations. Cy-ND successfully detected viscosity changes amidst acute alcohol-induced liver injury and liver ischemia-reperfusion injury.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fluorescent Dyes Limits: Animals / Humans Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2024 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fluorescent Dyes Limits: Animals / Humans Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2024 Document type: Article Affiliation country: Country of publication: