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The metabolic fuel of paroxysmal nocturnal haemoglobinuria.
Guarnera, Luca; Visconte, Valeria.
Affiliation
  • Guarnera L; Department of Translational Hematology & Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, USA.
  • Visconte V; Department of Biomedicine and Prevention, Tor Vergata University, Rome, Italy.
Br J Haematol ; 204(6): 2162-2164, 2024 Jun.
Article in En | MEDLINE | ID: mdl-38719212
ABSTRACT
Metabolic reprogramming has been investigated in haematological malignancies. To date, a few studies have analysed the metabolic profile of paroxysmal nocturnal haemoglobinuria (PNH). The study by Chen and colleagues sheds light on the involvement of metabolic changes in the proliferation of PNH clones. Commentary on Chen et al. The histone demethylase JMJD1C regulates CPS1 expression and promotes the proliferation of PNH clones through cell metabolic reprogramming. Br J Haematol 2024;2042468-2479.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemoglobinuria, Paroxysmal Limits: Humans Language: En Journal: Br J Haematol / Br. j. haematol / British journal of haematology Year: 2024 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemoglobinuria, Paroxysmal Limits: Humans Language: En Journal: Br J Haematol / Br. j. haematol / British journal of haematology Year: 2024 Document type: Article Affiliation country: Country of publication: