Prevalence of the cagA Virulence Factor Varies by Race Among Helicobacter pylori -Infected Patients Undergoing Upper Endoscopy.
Clin Transl Gastroenterol
; 15(6): e1, 2024 Jun 01.
Article
in En
| MEDLINE
| ID: mdl-38742743
ABSTRACT
INTRODUCTION:
We designed a race-conscious study to assess the presence of Helicobacter pylori v irulence factor cagA in a retrospective cohort of patients with active H. pylori infection.METHODS:
We compared cagA status by race in gastric tissue samples from 473 patients diagnosed with active H. pylori infection from 2015 to 2019.RESULTS:
H. pylori + Black patients were 2 times more likely to be cagA + than H. pylori + White patients (82% vs 36%, P < .0001).DISCUSSION:
Presence of cagA is common among endoscopy patients with active H. pylori infection; appropriate testing and treatment of H. pylori can both reduce gastric cancer risk and address health disparities.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bacterial Proteins
/
Helicobacter pylori
/
Helicobacter Infections
/
Virulence Factors
/
Antigens, Bacterial
Limits:
Adult
/
Aged
/
Female
/
Humans
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Male
/
Middle aged
Language:
En
Journal:
Cli. transl. gastroenterol
/
Clin Transl Gastroenterol
/
Clinical and translational gastroenterology
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: