Malignant melanoma in a 12-year-old boy 17 months after completing hepatoblastoma treatment.
Cancer Rep (Hoboken)
; 7(5): e2118, 2024 May.
Article
in En
| MEDLINE
| ID: mdl-38801212
ABSTRACT
BACKGROUND:
Melanoma is rare as a secondary malignant neoplasm among childhood cancer survivors. CASE We report a case of a 12-year-old boy who developed malignant melanoma with systemic metastases 17 months after completing treatment for hepatoblastoma. The diagnosis was made unexpectedly based on a bone marrow examination. The patient did not respond to immune checkpoint inhibitor therapy and died 6 weeks after being diagnosed with melanoma. Whole-exome sequencing to examine 103 genes associated with cancer predisposition did not identify any germ-line variants.CONCLUSION:
This case study provides a unique example of melanoma in a childhood cancer survivor following hepatoblastoma treatment but does not identify any candidate variant to link hepatoblastoma and melanoma.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Hepatoblastoma
/
Liver Neoplasms
/
Melanoma
Limits:
Child
/
Humans
/
Male
Language:
En
Journal:
Cancer Rep (Hoboken)
/
Cancer rep
/
Cancer reports
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: