Chronotherapy involving rosiglitazone regulates the phenotypic switch of vascular smooth muscle cells by shifting the phase of TNF-&#945; rhythm through triglyceride accumulation in macrophages.

Tian, Yu; Luan, Xuanyu; Yang, Kui

Chronotherapy involving rosiglitazone regulates the phenotypic switch of vascular smooth muscle cells by shifting the phase of TNF-α rhythm through triglyceride accumulation in macrophages.

Tian, Yu; Luan, Xuanyu; Yang, Kui.

Affiliation

Tian Y; School of Pharmacy, Wannan Medical College, Wuhu, Anhui, 241001. PR China.
Luan X; Department of Pharmacy, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui, 241001, PR China.
Yang K; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom.

Heliyon ; 10(10): e30708, 2024 May 30.

Article in En | MEDLINE | ID: mdl-38803898

Key words

Chronotherapy; Clock gene; Lipid metabolism; Macrophages; PPARÎ³ agonists; VSMCs phenotype switch

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Heliyon Year: 2024 Document type: Article Country of publication:

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Heliyon Year: 2024 Document type: Article Country of publication: