Your browser doesn't support javascript.
loading
Correlation between the triglyceride-glucose index and left ventricular global longitudinal strain in patients with chronic heart failure: a cross-sectional study.
Zhang, Shuai; Liu, Yan; Liu, Fangfang; Ye, Qing; Guo, Dachuan; Xu, Panpan; Wei, Tianhao; Zhang, Cheng; Lu, Huixia.
Affiliation
  • Zhang S; State Key Laboratory for Innovation and Transformation of Luobing Theory, Jinan, China.
  • Liu Y; Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Jinan, China.
  • Liu F; Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
  • Ye Q; State Key Laboratory for Innovation and Transformation of Luobing Theory, Jinan, China.
  • Guo D; Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Jinan, China.
  • Xu P; Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
  • Wei T; State Key Laboratory for Innovation and Transformation of Luobing Theory, Jinan, China.
  • Zhang C; Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Jinan, China.
  • Lu H; Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.
Cardiovasc Diabetol ; 23(1): 182, 2024 May 29.
Article in En | MEDLINE | ID: mdl-38811950
ABSTRACT

BACKGROUND:

Left ventricular global longitudinal strain (GLS) holds greater diagnostic and prognostic value than left ventricular ejection fraction (LVEF) in the heart failure (HF) patients. The triglyceride-glucose (TyG) index serves as a reliable surrogate for insulin resistance (IR) and is strongly associated with several adverse cardiovascular events. However, there remains a research gap concerning the correlation between the TyG index and GLS among patients with chronic heart failure (CHF).

METHOD:

427 CHF patients were included in the final analysis. Patient demographic information, along with laboratory tests such as blood glucose, lipids profiles, and echocardiographic data were collected. The TyG index was calculated as Ln [fasting triglyceride (TG) (mg/dL) × fasting plasma glucose (FPG) (mg/dL)/2].

RESULTS:

Among CHF patients, GLS was notably lower in the higher TyG index group compared to the lower TyG index group. Following adjustment for confounding factors, GLS demonstrated gradual decrease with increasing TyG index, regardless of the LVEF level and CHF classification.

CONCLUSION:

Elevated TyG index may be independently associated with more severe clinical left ventricular dysfunction in patients with CHF.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triglycerides / Blood Glucose / Biomarkers / Ventricular Function, Left / Ventricular Dysfunction, Left / Heart Failure Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Cardiovasc Diabetol Journal subject: ANGIOLOGIA / CARDIOLOGIA / ENDOCRINOLOGIA Year: 2024 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triglycerides / Blood Glucose / Biomarkers / Ventricular Function, Left / Ventricular Dysfunction, Left / Heart Failure Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Cardiovasc Diabetol Journal subject: ANGIOLOGIA / CARDIOLOGIA / ENDOCRINOLOGIA Year: 2024 Document type: Article Affiliation country: