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Redefining intestinal stemness: The emergence of a new ISC population.
Li, Mei-Lan; Sumigray, Kaelyn.
Affiliation
  • Li ML; Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA.
  • Sumigray K; Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA; Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06510, USA; Yale Cancer Center, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: kaelyn.sumigray@yale.edu.
Cell ; 187(12): 2900-2902, 2024 Jun 06.
Article in En | MEDLINE | ID: mdl-38848673
ABSTRACT
In tissue homeostasis, intestinal stem cells (ISCs) undergo continuous self-renewal to sustain rapid cellular turnover. In this issue of Cell, Capdevila et al.1 and Malagola, Vasciaveo, et al.2 identify a new ISC population in the upper crypt that can generate Lgr5+ stem cells during homeostasis.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Intestines Limits: Animals / Humans Language: En Journal: Cell Year: 2024 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Intestines Limits: Animals / Humans Language: En Journal: Cell Year: 2024 Document type: Article Affiliation country: