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Could the thick of retinal nerve fiber layer be a potential measure of axonal loss in hearing loss?
Celik, Elif K; Acar, Mutlu; Keseroglu, Kemal; Doluoglu, Sumeyra; Bayir, Omer; Mutlu, Murad; Saylam, Guleser.
Affiliation
  • Celik EK; Department of Otorhinolaryngology Head and Neck Surgery, University of Tokat Gaziosmanpasa, Tokat.
  • Acar M; Department of Ophthalmology, University of Health Sciences Diskapi Yildirim Beyazit Training and Research Hospital, Ankara.
  • Keseroglu K; Department of Otorhinolaryngology, University of Health Sciences Diskapi Yildirim Beyazit Training and Research Hospital, Ankara.
  • Doluoglu S; Department of Otorhinolaryngology Head and Neck Surgery, Ankara Etlik City Hospital, Ankara. Turkey.
  • Bayir O; Department of Otorhinolaryngology Head and Neck Surgery, Ankara Etlik City Hospital, Ankara. Turkey.
  • Mutlu M; Department of Otorhinolaryngology Head and Neck Surgery, Ankara Etlik City Hospital, Ankara. Turkey.
  • Saylam G; Department of Otorhinolaryngology Head and Neck Surgery, Ankara Etlik City Hospital, Ankara. Turkey.
Cir Cir ; 92(3): 324-330, 2024.
Article in En | MEDLINE | ID: mdl-38862104
ABSTRACT

OBJECTIVE:

The objective of the study is to compare the optic coherence tomography (OCT) parameters of the healthy and affected sides of patients with idiopathic sudden sensorineural hearing loss (ISSNHL) and to investigate the relationships between these and the improvement in hearing levels.

METHODS:

A bilateral eye evaluation of patients diagnosed with ISSNHL was performed with OCT. The ganglion cell complex (GCC) and retina nerve fiber layer (RNFL) thickness values were recorded and the differences between the two eyes were examined.

RESULTS:

An evaluation was made of 39 patients with a mean age of 44.82 ± 14.90 years. The RNFL thickness of the eyes was determined to be mean 89.87 ± 3.65 µm on the affected side and 103.87 ± 3.98 µm on the healthy control side (p = 0.0001). The mean GCC was determined to be mean 90.46 ± 3.49 µm on the affected side and 103.77 ± 3.96 µm on the healthy control side (p = 0.0001).

CONCLUSIONS:

A statistically significant difference was observed between the healthy and affected eyes of patients with ISSNHL with respect to mean GCC and mean RNFL thickness. OCT could be a useful technique for measuring this neural degeneration.
RESUMEN

OBJETIVO:

Comparar e investigar los parámetros de la tomografía de coherencia óptica (OCT) de los lados sanos y afectados de pacientes con pérdida auditiva neurosensorial súbita idiopática (PANSI).

MÉTODO:

La evaluación ocular bilateral de los pacientes diagnosticados con PANSI se realizó con OCT. Se registraron los valores de espesor del complejo de células ganglionares (CCG) y de la capa de fibras nerviosas de la retina (CFNR), y se examinaron las diferencias entre los dos ojos.

RESULTADOS:

Se evaluaron 39 pacientes, con una edad media de 44.82 ± 14.90 años. Se determinó que el grosor de la CFNR de los ojos era una media de 89.87 ± 3.65 µm en el lado afectado y 103.87 ± 3.98 µm en el lado de control sano (p = 0.0001). Se determinó que el CCG medio era 90.46 ± 3.49 µm en el lado afectado y 103.77 ± 3.96 µm en el lado de control sano (p = 0.0001).

CONCLUSIONES:

Se encontró una diferencia estadísticamente significativa entre los ojos sanos y afectados de pacientes con PANSI con respecto al CCG medio y al espesor medio de la CFNR. La OCT podría ser una técnica útil para medir esta degeneración neuronal.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Tomography, Optical Coherence / Nerve Fibers Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Cir Cir Year: 2024 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Tomography, Optical Coherence / Nerve Fibers Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Cir Cir Year: 2024 Document type: Article
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