Comprehensive Overview of Candida auris: An Emerging Multidrug-Resistant Fungal Pathogen.
J Microbiol Biotechnol
; 34(7): 1365-1375, 2024 Jul 28.
Article
in En
| MEDLINE
| ID: mdl-38881183
ABSTRACT
The rise of Candida auris, a multidrug-resistant fungal pathogen, across more than 40 countries, has signaled an alarming threat to global health due to its significant resistance to existing antifungal therapies. Characterized by its rapid spread and robust drug resistance, C. auris presents a critical challenge in managing infections, particularly in healthcare settings. With research on its biological traits and genetic basis of virulence and resistance still in the early stages, there is a pressing need for a concerted effort to understand and counteract this pathogen. This review synthesizes current knowledge on the epidemiology, biology, genetic manipulation, pathogenicity, diagnostics, and resistance mechanisms of C. auris, and discusses future directions in research and therapeutic development. By exploring the complexities surrounding C. auris, we aim to underscore the importance of advancing research to devise effective control and treatment strategies.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Candidiasis
/
Drug Resistance, Multiple, Fungal
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Candida auris
/
Antifungal Agents
Limits:
Animals
/
Humans
Language:
En
Journal:
J Microbiol Biotechnol
Year:
2024
Document type:
Article
Country of publication: