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Pancreas-specific immune-related adverse events in patients with lung cancer: a case series study.
Jia, Liu; Yuequan, Shi; Jian, Fang; Hongmin, Lu; Yongjie, Shui; Xiaoyan, Liu; Minjiang, Chen; Yan, Xu; Mengzhao, Wang.
Affiliation
  • Jia L; Department of Respiratory & Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
  • Yuequan S; Department of Respiratory & Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
  • Jian F; Department of Thoracic Oncology II, Key Laboratory of Carcinogenesis & Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing, China.
  • Hongmin L; Department of Oncology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
  • Yongjie S; Department of Radiation Oncology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Xiaoyan L; Department of Respiratory & Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
  • Minjiang C; Department of Respiratory & Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
  • Yan X; Department of Respiratory & Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
  • Mengzhao W; Department of Respiratory & Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Immunotherapy ; : 1-8, 2024 Jun 18.
Article in En | MEDLINE | ID: mdl-38888461
ABSTRACT
Immune-related adverse events (irAEs) are one of the key concerns in cancer patients treated with immune checkpoint inhibitors (ICIs). Among the various irAEs, pancreas-specific irAE is a rare but special one with a variety of manifestations, such as pancreatic enzymes elevation, pancreatitis as well as diabetes. The current study reported 22 pancreas-specific irAEs in 21 patients with lung cancer, including pancreatic injury in 13 patients, pancreatitis in four patients and diabetes mellitus in five patients.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Immunotherapy Journal subject: ALERGIA E IMUNOLOGIA / TERAPEUTICA Year: 2024 Document type: Article Affiliation country: Publication country: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Immunotherapy Journal subject: ALERGIA E IMUNOLOGIA / TERAPEUTICA Year: 2024 Document type: Article Affiliation country: Publication country: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM