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Pathological biopsy strategy by regulating intracellular ROS to precisely differentiate cancer cells from diseased tissues.
Zhang, Shaoxiong; Liao, Chunyan; Wei, Wei; Zhang, Shiyong.
Affiliation
  • Zhang S; College of Chemistry and National Engineering Research Center for Biomaterials, Sichuan University, 29 Wangjiang Road, Chengdu 610064, China. szhang@scu.edu.cn.
  • Liao C; College of Chemistry and National Engineering Research Center for Biomaterials, Sichuan University, 29 Wangjiang Road, Chengdu 610064, China. szhang@scu.edu.cn.
  • Wei W; Department of Emergency Medicine, West China Hospital, Sichuan University, No. 37, Guoxue Lane, Chengdu 610041, China. ww8075@126.com.
  • Zhang S; College of Chemistry and National Engineering Research Center for Biomaterials, Sichuan University, 29 Wangjiang Road, Chengdu 610064, China. szhang@scu.edu.cn.
Chem Commun (Camb) ; 60(56): 7172-7175, 2024 Jul 09.
Article in En | MEDLINE | ID: mdl-38904347
ABSTRACT
We have developed an innovative pathological biopsy strategy by expanding the differences of ROS levels among cancer cells, inflammatory cells and normal cells using cross-linked lipoic acid vesicles loaded with vitamin C (VC@cLAVs), combined with chemiluminescence imaging technology. By analyzing the different trends of intracellular chemiluminescence intensity, the three types of cells were quickly and accurately differentiated from diseased tissues, thus holding clinical tumor diagnostic potential.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ascorbic Acid / Thioctic Acid / Reactive Oxygen Species Limits: Humans Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2024 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ascorbic Acid / Thioctic Acid / Reactive Oxygen Species Limits: Humans Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2024 Document type: Article Affiliation country: