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Adult microglial TGFß1 is required for microglia homeostasis via an autocrine mechanism to maintain cognitive function in mice.
Bedolla, Alicia; Wegman, Elliot; Weed, Max; Stevens, Messiyah K; Ware, Kierra; Paranjpe, Aditi; Alkhimovitch, Anastasia; Ifergan, Igal; Taranov, Aleksandr; Peter, Joshua D; Gonzalez, Rosa Maria Salazar; Robinson, J Elliott; McClain, Lucas; Roskin, Krishna M; Greig, Nigel H; Luo, Yu.
Affiliation
  • Bedolla A; Department of Molecular and Cellular Biosciences, University of Cincinnati, Cincinnati, OH, USA.
  • Wegman E; Neuroscience Graduate Program, University of Cincinnati, Cincinnati, OH, USA.
  • Weed M; Department of Molecular and Cellular Biosciences, University of Cincinnati, Cincinnati, OH, USA.
  • Stevens MK; Department of Molecular and Cellular Biosciences, University of Cincinnati, Cincinnati, OH, USA.
  • Ware K; Department of Psychology, Vanderbilt University, Nashville, TN, USA.
  • Paranjpe A; Department of Molecular and Cellular Biosciences, University of Cincinnati, Cincinnati, OH, USA.
  • Alkhimovitch A; Information Services for Research, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.
  • Ifergan I; Department of Molecular and Cellular Biosciences, University of Cincinnati, Cincinnati, OH, USA.
  • Taranov A; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Peter JD; Department of Molecular and Cellular Biosciences, University of Cincinnati, Cincinnati, OH, USA.
  • Gonzalez RMS; Neuroscience Graduate Program, University of Cincinnati, Cincinnati, OH, USA.
  • Robinson JE; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • McClain L; Department of Molecular and Cellular Biosciences, University of Cincinnati, Cincinnati, OH, USA.
  • Roskin KM; Neuroscience Graduate Program, University of Cincinnati, Cincinnati, OH, USA.
  • Greig NH; Department of Molecular and Cellular Biosciences, University of Cincinnati, Cincinnati, OH, USA.
  • Luo Y; Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Nat Commun ; 15(1): 5306, 2024 Jun 21.
Article in En | MEDLINE | ID: mdl-38906887
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cognition / Microglia / Mice, Knockout / Autocrine Communication / Transforming Growth Factor beta1 / Homeostasis Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2024 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cognition / Microglia / Mice, Knockout / Autocrine Communication / Transforming Growth Factor beta1 / Homeostasis Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2024 Document type: Article Affiliation country: Country of publication: