Current research progress, opportunities, and challenges of Limosillactobacillus reuteri-based probiotic dietary strategies.
Crit Rev Food Sci Nutr
; : 1-21, 2024 Jun 26.
Article
in En
| MEDLINE
| ID: mdl-38920093
ABSTRACT
Limosillactobacillus reuteri (L. reuteri), a type of Lactobacillus spp., stands out as the most extensively researched probiotic. Its remarkable intestinal adhesion has led to widespread applications in both the food and medical sectors. Notably, recent research highlights the probiotic efficacy of L. reuteri sourced from breast milk, particularly in influencing social behavior and mitigating atopic dermatitis. In this review, our emphasis is on surveying recent literature regarding the promotion of host's health by L. reuteri. We aim to provide a concise summary of the latest regulatory effects and potential mechanisms attributed to L. reuteri in the realms of metabolism, brain- and immune-related functions. The mechanism through which L. reuteri promotes host health by modulating the intestinal microenvironment primarily involves promoting intestinal epithelial renewal, bolstering intestinal barrier function, regulating gut microbiota and its metabolites, and suppressing inflammation and immune responses. Additionally, this review delves into new technologies, identifies shortcomings, and addresses challenges in current L. reuteri research. Finally, the application prospects of L. reuteri are provided. Therefore, a better understanding of the role and mechanisms of L. reuteri will contribute significantly to the development of new probiotic functional foods and enable precise, targeted interventions for various diseases.
Full text:
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Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Crit Rev Food Sci Nutr
Journal subject:
CIENCIAS DA NUTRICAO
Year:
2024
Document type:
Article
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