Models of sepsis-induced acute kidney injury.
Life Sci
; 352: 122873, 2024 Sep 01.
Article
in En
| MEDLINE
| ID: mdl-38950643
ABSTRACT
Sepsis-induced acute kidney injury (S-AKI) is one of the most serious life-threatening complications of sepsis. The pathogenesis of S-AKI is complex and there is no effective specific treatment. Therefore, it is crucial to choose suitable preclinical models that are highly similar to human S-AKI to study the pathogenesis and drug treatment. In this review, we summarized recent advances in the development models of S-AKI, providing reference for the reasonable selection of experimental models as basic research and drug development of S-AKI.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sepsis
/
Disease Models, Animal
/
Acute Kidney Injury
Limits:
Animals
/
Humans
Language:
En
Journal:
Life Sci
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: