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Unraveling the effect of micro/nanoplastics on the occurrence and horizontal transfer of environmental antibiotic resistance genes: Advances, mechanisms and future prospects.
Shi, Jianhong; Sun, Chaoli; An, Tingxuan; Jiang, Changhai; Mei, Shenglong; Lv, Baoyi.
Affiliation
  • Shi J; College of Ocean Science and Engineering, Shanghai Maritime University, Shanghai 201306, China.
  • Sun C; College of Ocean Science and Engineering, Shanghai Maritime University, Shanghai 201306, China.
  • An T; College of Ocean Science and Engineering, Shanghai Maritime University, Shanghai 201306, China.
  • Jiang C; College of Ocean Science and Engineering, Shanghai Maritime University, Shanghai 201306, China.
  • Mei S; College of Ocean Science and Engineering, Shanghai Maritime University, Shanghai 201306, China.
  • Lv B; College of Ocean Science and Engineering, Shanghai Maritime University, Shanghai 201306, China; International Joint Research Center for Persistent Toxic Substances (IJRC-PTS), Shanghai Maritime University, Shanghai 201306, China. Electronic address: bylv@shmtu.edu.cn.
Sci Total Environ ; 947: 174466, 2024 Oct 15.
Article in En | MEDLINE | ID: mdl-38964386
ABSTRACT
Microplastics can not only serve as vectors of antibiotic resistance genes (ARGs), but also they and even nanoplastics potentially affect the occurrence of ARGs in indigenous environmental microorganisms, which have aroused great concern for the development of antibiotic resistance. This article specifically reviews the effects of micro/nanoplastics (concentration, size, exposure time, chemical additives) and their interactions with other pollutants on environmental ARGs dissemination. The changes of horizontal genes transfer (HGT, i.e., conjugation, transformation and transduction) of ARGs caused by micro/nanoplastics were also summarized. Further, this review systematically sums up the mechanisms of micro/nanoplastics regulating HGT process of ARGs, including reactive oxygen species production, cell membrane permeability, transfer-related genes expression, extracellular polymeric substances production, and ARG donor-recipient adsorption/contaminants adsorption/biofilm formation. The underlying mechanisms in changes of bacterial communities induced by micro/nanoplastics were also discussed as it was an important factor for structuring the profile of ARGs in the actual environment, including causing environmental stress, providing carbon sources, forming biofilms, affecting pollutants distribution and environmental factors. This review contributes to a systematical understanding of the potential risks of antibiotic resistance dissemination caused by micro/nanoplastics and provokes thinking about perspectives for future research and the management of micro/nanoplastics and plastics.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance, Microbial / Gene Transfer, Horizontal / Microplastics Language: En Journal: Sci Total Environ / Sci. total environ / Science of the total environment Year: 2024 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance, Microbial / Gene Transfer, Horizontal / Microplastics Language: En Journal: Sci Total Environ / Sci. total environ / Science of the total environment Year: 2024 Document type: Article Affiliation country: Country of publication: