Effective removal of gadolinium with hemodialysis in a dog with severe acute on chronic kidney injury.
J Vet Emerg Crit Care (San Antonio)
; 34(4): 406-411, 2024.
Article
in En
| MEDLINE
| ID: mdl-38971980
ABSTRACT
OBJECTIVE:
To describe the use of intermittent hemodialysis (IHD) to remove gadolinium (28.1 mg/kg dose) in a dog with severe kidney disease. CASESUMMARY:
A 12-year-old neutered female Yorkshire Terrier presented with severe acute-on-chronic kidney injury and concurrent neurological signs. The dog received extracorporeal therapy as part of management. Uremia improved after hemodialysis, but central nervous system signs persisted; therefore, a contrast-enhanced magnetic resonance imaging was performed, immediately followed by IHD. Two IHD treatments with a low-flux dialyzer were performed 1.5 and 25.75 hours after administration of gadolinium, with almost complete removal of gadolinium. More than 96% of gadolinium was removed with a single treatment. NEW OR UNIQUE INFORMATION PROVIDED Extracorporeal therapy is effective at removing gadolinium-based chelated contrast agents and could be considered if magnetic resonance imaging is indicated in a patient with substantial kidney impairment. Alternatively, newer contrast agents that have been deemed safer in this patient population could be used.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Renal Dialysis
/
Contrast Media
/
Dog Diseases
/
Gadolinium
Limits:
Animals
Language:
En
Journal:
J Vet Emerg Crit Care (San Antonio)
Journal subject:
MEDICINA DE EMERGENCIA
/
MEDICINA VETERINARIA
/
TERAPIA INTENSIVA
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: