Skin deep: Epithelial cell metabolism and chronic skin inflammation.
Immunity
; 57(7): 1451-1453, 2024 Jul 09.
Article
in En
| MEDLINE
| ID: mdl-38986439
ABSTRACT
Skin inflammation is potentiated by coordinated epithelial and immune cell metabolism. In this issue of Immunity, Subudhi and Konieczny et al. delineate how HIF1α regulates epithelial cell glycolysis during psoriasis. In turn, lactate is a byproduct that augments type 17 γδ T cell responses to sustain inflammatory skin disease.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Psoriasis
/
Skin
/
Epithelial Cells
/
Hypoxia-Inducible Factor 1, alpha Subunit
/
Glycolysis
Limits:
Animals
/
Humans
Language:
En
Journal:
Immunity
Journal subject:
ALERGIA E IMUNOLOGIA
Year:
2024
Document type:
Article
Affiliation country: