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Agent-based model predicts that layered structure and 3D movement work synergistically to reduce bacterial load in 3D in vitro models of tuberculosis granuloma.
Petrucciani, Alexa; Hoerter, Alexis; Kotze, Leigh; Du Plessis, Nelita; Pienaar, Elsje.
Affiliation
  • Petrucciani A; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, United States of America.
  • Hoerter A; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, United States of America.
  • Kotze L; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medical and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Du Plessis N; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medical and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Pienaar E; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, United States of America.
PLoS Comput Biol ; 20(7): e1012266, 2024 Jul.
Article in En | MEDLINE | ID: mdl-38995971
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Load / Granuloma / Mycobacterium tuberculosis Limits: Humans Language: En Journal: PLoS Comput Biol Journal subject: BIOLOGIA / INFORMATICA MEDICA Year: 2024 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Load / Granuloma / Mycobacterium tuberculosis Limits: Humans Language: En Journal: PLoS Comput Biol Journal subject: BIOLOGIA / INFORMATICA MEDICA Year: 2024 Document type: Article Affiliation country: Country of publication: