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A novel monoclonal antibody generated by immunization with granular tau oligomers binds to tau aggregates at 423-430 amino acid sequence.
Soeda, Yoshiyuki; Hayashi, Emi; Nakatani, Naoko; Ishigaki, Shinsuke; Takaichi, Yuta; Tachibana, Taro; Riku, Yuichi; Chambers, James K; Koike, Riki; Mohammad, Moniruzzaman; Takashima, Akihiko.
Affiliation
  • Soeda Y; Laboratory for Alzheimer's Disease, Department of Life Science, Faculty of Science, Gakushuin University, 1-5-1 Mejiro, Toshima-ku, Tokyo, 171-8588, Japan. soeday7188@gmail.com.
  • Hayashi E; Cell Engineering Corporation, 5-12-14 Nishinakajima, Yodogawa-ku, Osaka, 532-0011, Japan.
  • Nakatani N; Cell Engineering Corporation, 5-12-14 Nishinakajima, Yodogawa-ku, Osaka, 532-0011, Japan.
  • Ishigaki S; Department of Diagnostics and Therapeutics for Brain Disease, Molecular Neuroscience Research Center, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Takaichi Y; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
  • Tachibana T; Cell Engineering Corporation, 5-12-14 Nishinakajima, Yodogawa-ku, Osaka, 532-0011, Japan.
  • Riku Y; Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology, Osaka Metropolitan University, 3-3-138 Sugimoto, Sumiyoshi-ku, Osaka-shi, Osaka, 558-0022, Japan.
  • Chambers JK; Institute for Medical Science of Aging, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
  • Koike R; Department of Neurology, Nagoya University, 65 Tsurumai, Showa, Nagoya, Aichi, 466-8550, Japan.
  • Mohammad M; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
  • Takashima A; Laboratory for Alzheimer's Disease, Department of Life Science, Faculty of Science, Gakushuin University, 1-5-1 Mejiro, Toshima-ku, Tokyo, 171-8588, Japan.
Sci Rep ; 14(1): 16391, 2024 07 26.
Article in En | MEDLINE | ID: mdl-39060263
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mice, Transgenic / Tau Proteins / Alzheimer Disease / Antibodies, Monoclonal Limits: Aged / Animals / Female / Humans / Male Language: En Journal: Sci Rep Year: 2024 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mice, Transgenic / Tau Proteins / Alzheimer Disease / Antibodies, Monoclonal Limits: Aged / Animals / Female / Humans / Male Language: En Journal: Sci Rep Year: 2024 Document type: Article Affiliation country: Country of publication: