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A novel selective NLRP3 inhibitor shows disease-modifying potential in animal models of Parkinson's disease.
Chatterjee, Abhijit; Mohapatra, Jogeswar; Sharma, Manoranjan; Jha, Abhishek; Patro, Randeep; Das, Debajeet; Patel, Hiren; Patel, Harilal; Chaudhari, Jaimin; Borda, Nilesh; Viswanathan, Kasinath; Sharma, Bhavesh; Bhavsar, Harsh; Patel, Ashvin; Ranvir, Ramchandra; Sundar, Rajesh; Agarwal, Sameer; Jain, Mukul.
Affiliation
  • Chatterjee A; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India. Electronic address: abhijitchatterjee@zyduslife.com.
  • Mohapatra J; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Sharma M; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Jha A; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Patro R; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Das D; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Patel H; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Patel H; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Chaudhari J; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Borda N; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Viswanathan K; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Sharma B; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Bhavsar H; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Patel A; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Ranvir R; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Sundar R; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Agarwal S; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
  • Jain M; Zydus Research Centre, Zydus Lifesciences Limited, Sharkhej-Bavla NH No. 8A, Village Moraiya, Changodar, Ahmedabad 382 213, Gujarat, India.
Brain Res ; 1842: 149129, 2024 Nov 01.
Article in En | MEDLINE | ID: mdl-39074525
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Disease Models, Animal / NLR Family, Pyrin Domain-Containing 3 Protein / Mice, Inbred C57BL Limits: Animals / Humans / Male Language: En Journal: Brain Res Year: 2024 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Disease Models, Animal / NLR Family, Pyrin Domain-Containing 3 Protein / Mice, Inbred C57BL Limits: Animals / Humans / Male Language: En Journal: Brain Res Year: 2024 Document type: Article Country of publication: