Advancements in the Transdermal Drug Delivery Systems Utilizing Microemulsion-based Gels.
Curr Pharm Des
; 2024 Aug 01.
Article
in En
| MEDLINE
| ID: mdl-39092731
ABSTRACT
Microemulsion gel, as a promising transdermal nanoparticle delivery system, addresses the limitations of microemulsions and enhances their performance in drug delivery and release. This article aims to discuss the advantages of microemulsion gel, including improved drug bioavailability, reduced drug irritation, enhanced drug penetration and skin adhesion, and increased antimicrobial properties. It explores the methods for selecting microemulsion formulations and the general processes of microemulsion preparation, as well as commonly used oil phases, surfactants, and co-surfactants. Additionally, the biomedical applications of microemulsion gel in treating conditions, such as acne and psoriasis, are also discussed. Overall, this article elucidates the significant potential of microemulsion gel in topical drug delivery, providing insights into future development and clinical applications.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Curr Pharm Des
Journal subject:
FARMACIA
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: