Phytocannabinoid-like meroterpenoids from twigs and leaves of Rhododendron spinuliferum.
Phytochemistry
; 228: 114241, 2024 Aug 08.
Article
in En
| MEDLINE
| ID: mdl-39122160
ABSTRACT
Six pairs of previously undescribed enantiomeric phytocannabinoid-like meroterpenoids, (±)-spinulinoids AâF, and two naturally occurring compounds, (+)-rhododaurichromanic acid A and (E)-4-((3,7-dimethylocta-2,6-dien-1-yl)oxy)benzoic acid, together with one known congener, (-)-rhododaurichromanic acid A, were obtained from the twigs and leaves of Rhododendron spinuliferum. Their structures were established by their extensive spectral data (NMR and HRESIMS), ECD calculations, and single-crystal X-ray diffraction data. Spinulinoids A and B are unprecedented phytocannabinoid-like meroterpenoids constructed by the resorcinol moiety and a ß-bisabolene unit, whereas spinulinoid C represents a rare adduct of quinone and ß-bisabolene with a tricyclic 6/6/6 ring system.
Full text:
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Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Phytochemistry
Year:
2024
Document type:
Article