Prognostic risk factors for pyogenic liver abscess caused by Klebsiella pneumoniae.
BMC Gastroenterol
; 24(1): 298, 2024 Sep 03.
Article
in En
| MEDLINE
| ID: mdl-39227812
ABSTRACT
BACKGROUND:
Pyogenic liver abscess (PLA) caused by Klebsiella pneumoniae can vary in severity, and several risk factors for the development of organ dysfunction in PLA have been implicated. However, few studies to date have explored the most common risk factors for clinical severity.METHODS:
We conducted a study on patients with PLA caused by Klebsiella pneumoniae between February 2013 and December 2022.Using logistic regression analysis, we sought to identify factors associated with positive blood culture, septic shock, and intensive care unit (ICU) admission.RESULTS:
After included 200 patients, we found that an elevated procalcitonin (PCT) level (p = 0.03), higher glucose level (p = 0.03), and lower total cholesterol (TC) level (p = 0.01) were associated with a higher likelihood of positive blood bacteriological culture. Additionally, an increased PCT level (p = 0.02) and lower TC level (p < 0.01) were associated with an elevated risk of septic shock. Furthermore, a higher PCT level (p < 0.01) was associated with a higher probability of ICU admission.CONCLUSION:
In patients with PLA caused by Klebsiella pneumoniae, the PCT, glucose, and TC levels were found to be associated with positive blood culture, septic shock, and ICU admission.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Shock, Septic
/
Klebsiella Infections
/
Cholesterol
/
Liver Abscess, Pyogenic
/
Intensive Care Units
/
Klebsiella pneumoniae
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
BMC Gastroenterol
Journal subject:
GASTROENTEROLOGIA
Year:
2024
Document type:
Article
Country of publication: