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Impact of the COVID-19 pandemic on treatment of patients with acute myeloid leukaemia in India.
Philip, Chepsy; Selvarajan, Sushil; Nayak, Lingaraj; Jain, Hasmukh; Kulkarni, Uday; Samuel, Prasanna; Agrawal, Narendra; Kayal, Smita; Mishra, Kundan; Pavitra, D S; Jayachandran, P K; Bala, Stalin Chowdary; Raghavan, Vineetha; Paul, Mobin; Singh, Jagdeep; Sreeraj, V; Mujumdar, Swaratika; Nayak, Akshatha; Prakash, Om; Barath, U; Dharmaraj, Aravind; Rajendra, Akhil; Thorat, Jayashree; Bagal, Bhausaheb; Abraham, Aby; Bhurani, Dinesh; Ganesan, Prasanth; Sengar, Manju; Mathews, Vikram.
Affiliation
  • Philip C; Believers Church Medical College Hospital, Thiruvalla, India.
  • Selvarajan S; Christian Medical College, Vellore, India.
  • Nayak L; Tata Memorial Hospital, Mumbai, India.
  • Jain H; Tata Memorial Hospital, Mumbai, India.
  • Kulkarni U; Christian Medical College, Vellore, India.
  • Samuel P; Clinical Data Management Services, Department of Biostatistics, CMC Vellore, Vellore, India.
  • Agrawal N; Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
  • Kayal S; Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India.
  • Mishra K; Army Hospital Research and Referral, Delhi, India.
  • Pavitra DS; Christian Medical College & Hospital, Ludhiana, India.
  • Jayachandran PK; Cancer Institute (WIA), Chennai, India.
  • Bala SC; Nizam's Institute of Medical Sciences (NIMS), Hyderabad, India.
  • Raghavan V; Malabar Cancer Centre, Thalassery, India.
  • Paul M; Rajagiri Hospital, Aluva, India.
  • Singh J; Dayanand Medical College and Hospital, Ludhiana, India.
  • Sreeraj V; Amala Cancer Institute, Amala Institute of Medical Sciences, Thrissur, India.
  • Mujumdar S; MS Ramaiah Medical College and Hospital, Bangalore, India.
  • Nayak A; Mazumdar Shaw Medical Center, Narayana Hrudayalaya Hospital, Bangalore, India.
  • Prakash O; Clinical Data Management Services, Department of Biostatistics, CMC Vellore, Vellore, India.
  • Barath U; Clinical Data Management Services, Department of Biostatistics, CMC Vellore, Vellore, India.
  • Dharmaraj A; Clinical Data Management Services, Department of Biostatistics, CMC Vellore, Vellore, India.
  • Rajendra A; Tata Memorial Hospital, Mumbai, India.
  • Thorat J; Tata Memorial Hospital, Mumbai, India.
  • Bagal B; Tata Memorial Hospital, Mumbai, India.
  • Abraham A; Christian Medical College, Vellore, India.
  • Bhurani D; Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
  • Ganesan P; Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India.
  • Sengar M; Tata Memorial Hospital, Mumbai, India.
  • Mathews V; Christian Medical College, Vellore, India.
Br J Haematol ; 2024 Sep 16.
Article in En | MEDLINE | ID: mdl-39279532
ABSTRACT
During the COVID-19 pandemic, our findings highlight changes in AML management strategies in India. There was a decrease in overall patient registrations, particularly at large referral centers, while smaller centers saw an increase, reflecting a shift towards more localized care. This shift was accompanied by a rise in the use of hypomethylating agents (HMAs). Despite these changes, survival outcomes remained comparable to pre-pandemic levels, likely due to improved infection control measures and maintaining treatment protocols. Our study concludes that standard AML care remained feasible during the pandemic, emphasizing the importance of continuing treatment for eligible patients even in times of crisis.

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Br J Haematol Year: 2024 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Br J Haematol Year: 2024 Document type: Article Affiliation country: Country of publication: