Molecular Characteristics and Expression of TKTL1 in Germ Cells: Implications for Nontumour Cell Research.
Reprod Domest Anim
; 59(9): e14723, 2024 Sep.
Article
in En
| MEDLINE
| ID: mdl-39311634
ABSTRACT
TKTL1 is a crucial regulatory enzyme in the pentose phosphate pathway (PPP) and plays a significant role in energy synthesis. It is expressed in various tumour tissues, with its expression level closely associated with tumour invasion, metastasis and prognosis. Recent studies utilising proteomic analysis and other methods have highlighted the noteworthy expression of the TKTL1 gene in germ cells, particularly in spermatogonia and ovarian cells. Consequently, this article reviews the molecular characteristics of TKTL1 and its expression in germ cells to provide a reference for research on TKTL1 beyond tumour cells.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Transketolase
Limits:
Animals
/
Female
/
Humans
/
Male
Language:
En
Journal:
Reprod Domest Anim
Journal subject:
MEDICINA REPRODUTIVA
/
MEDICINA VETERINARIA
Year:
2024
Document type:
Article
Affiliation country:
Country of publication: