Acetylation phenotypes and environmental chemical exposure of people with idiopathic systemic lupus erythematosus.
Arthritis Rheum
; 36(7): 971-3, 1993 Jul.
Article
in En
| MEDLINE
| ID: mdl-8318043
ABSTRACT
OBJECTIVE:
To test the hypotheses that there is an excess percentage of slow acetylators among patients with idiopathic systemic lupus erythematosus (SLE) and that these patients had excessive exposure to environmental amines and hydrazines before the onset of illness.METHODS:
Case-control study with structured interview and acetylation phenotyping.RESULTS:
No excess proportion of slow acetylators or environmental amine exposure was found.CONCLUSION:
Slow acetylation phenotype and exposure to environmental amines are not principal causes of idiopathic SLE.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Environmental Exposure
/
Amines
/
Lupus Erythematosus, Systemic
Type of study:
Etiology_studies
/
Observational_studies
/
Qualitative_research
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Arthritis Rheum
Year:
1993
Document type:
Article