Screening psychiatric admissions for anticardiolipin antibody.
Psychiatry Res
; 58(1): 83-8, 1995 Sep 08.
Article
in En
| MEDLINE
| ID: mdl-8539315
ABSTRACT
Anticardiolipin antibody (aCL) may provide an instrument for screening in neuropsychiatric syndromes due to cerebral ischemia. Thirty-five psychiatric patients, aCL-positive on admission, were matched against aCL-negative patients. Their clinical records on admission and after 2-years of follow-up were analyzed without knowledge of aCL results. An inventory was made of cerebrovascular and systemic vascular symptoms. In 13 out of 35 aCL-positive cases, vascular morbidity, suggesting ischemic causes of central nervous system pathology, could be demonstrated during follow-up and none in the comparison group. No correlation was found, however, between Hachinski ischemic scores on admission and aCL-positivity. Yet, if only on the basis of increased incidence of subsequent ischemia, the aCL-IgG/M isotype appears to be a valuable predictor of vascular neuropsychiatric symptoms.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Patient Admission
/
Dementia, Vascular
/
Mass Screening
/
Antibodies, Anticardiolipin
/
Neurocognitive Disorders
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Psychiatry Res
Year:
1995
Document type:
Article
Affiliation country: