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Effects of eicosanoids on parameters in isolated rat hepatocytes and isolated rat hepatocyte couplets: protective effects of eicosanoid receptor antagonists.
Hutchinson, S M; Hammond, T G; Coleman, R; Horton, A A.
Affiliation
  • Hutchinson SM; School of Biochemistry, University of Birmingham, Edgbaston, UK.
J Lipid Mediat Cell Signal ; 15(3): 249-54, 1997 Mar.
Article in En | MEDLINE | ID: mdl-9041475
ABSTRACT
A number of eicosanoids caused plasma membrane blebbing in hepatocytes and this could be inhibited in a dose-dependent fashion by the receptor antagonists AH6809 and ICI 192605. The pattern of effectiveness of eicosanoids interfering with canalicular vacuole accumulation in hepatocyte couplets differed from that causing blebbing; the two most effective eicosanoids here were PGD2 and PGF2 alpha.
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Collection: 01-internacional Database: MEDLINE Main subject: Eicosanoids / Receptors, Eicosanoid / Xanthones / Liver Limits: Animals Language: En Journal: J Lipid Mediat Cell Signal Journal subject: BIOQUIMICA Year: 1997 Document type: Article Affiliation country:
Search on Google
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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Eicosanoids / Receptors, Eicosanoid / Xanthones / Liver Limits: Animals Language: En Journal: J Lipid Mediat Cell Signal Journal subject: BIOQUIMICA Year: 1997 Document type: Article Affiliation country: