A study of tolerance in a concordant xenograft model.
Transplant Proc
; 29(1-2): 923-4, 1997.
Article
in En
| MEDLINE
| ID: mdl-9123588
ABSTRACT
Antibody-mediated rejection appears to constitute the major difference between concordant xenografts and allografts in nonhuman primates. Consistent with its known effect on antibody responses, 5-7 addition of DSG to the conditioning regimen has extended concordant primate xenograft survival for up to 6 months after discontinuation of conventional immunosuppression. In contrast to our observations in recipients of renal allografts, donor-specific skin graft rejection can occur and even in long-term recipients may induce rejection of a previously accepted renal xenograft.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Transplantation, Heterologous
/
Bone Marrow Transplantation
/
Kidney Transplantation
/
Graft Rejection
Limits:
Animals
Language:
En
Journal:
Transplant Proc
Year:
1997
Document type:
Article
Affiliation country: