T1 rho dispersion imaging of head and neck tumors: a comparison to spin lock and magnetization transfer techniques.
J Magn Reson Imaging
; 7(5): 873-9, 1997.
Article
in En
| MEDLINE
| ID: mdl-9307914
ABSTRACT
The potential of T1 rho dispersion, spin lock (SL), and magnetization transfer (MT) techniques to differentiate benign and malignant head and neck tumors was evaluated. Twenty-four patients with pathologically verified head and neck tumors were studied with a .1-T MR imager. T1 rho dispersion effect was defined as 1 -(intensity with lower locking field amplitude/intensity with higher locking field amplitude). T1 rho dispersion effects were higher for malignant than benign tumors (P = .001). With T1 rho dispersion effect .14 as the threshold, sensitivity for detecting a malignant tumor was 91%, specificity was 77%, and accuracy was 83%. A strong correlation between T1 rho dispersion effects and SL effects and between T1 rho dispersion effects and MT effects in the head and neck tumors was found (r = .87, P < .001 and r = .90, P < .001, respectively). High T1 rho dispersion effects are not specific indicators of malignancy, because chronic infections, some benign tumors, and malignancies may overlap. Low T1 rho dispersion effect values are characteristic of a benign tumor.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Magnetic Resonance Imaging
/
Image Enhancement
/
Head and Neck Neoplasms
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
En
Journal:
J Magn Reson Imaging
Journal subject:
DIAGNOSTICO POR IMAGEM
Year:
1997
Document type:
Article
Affiliation country: