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Application of propofol wada test and function magnetic resonance imaging in verbal memory lateralization evaluation of patients with temporal lobe epilepsy / 中华神经医学杂志
Chinese Journal of Neuromedicine ; (12): 691-695, 2013.
Article in Zh | WPRIM | ID: wpr-1033807
Responsible library: WPRO
ABSTRACT
Objective To compare the consistency and efficiency on predicting preoperative memory lateralization of left temporal lobe epilepsy patients using propofol wada test and function magnetic resonance imaging (fMRI).Methods Eight patients with left anterior temporal lobectomy (L-ATL),were chosen in our study and performed preoperative language and memory lateralization assessment by fMRI and propofol Wada test; combined with the pre-postoperative Wechsler memory or intelligence results,the consistency and efficiency of these two methods on evaluating the memory lateralization of left temporal lobe epilepsy patients were compared.Results The concordance of medial temporal lobe lateralization and vocabulary hemispheric lateralization by fMRI was 57% and 71.4%,respectively,as compared with those results of Wada test.Preoperative fMRI memory lateralization was significantly correlated with postoperative intelligence quotient,verbal memory and memory quotient change,while the post-preoperative changes were insignificantly related to Wada LI.Conclusion The consistency is different on account of the way of selecting regions of interest between preoperative propofol Wada test and verbal memory fMRI.The sensitivity of predicting postoperative vebal memory changed by fMRI is higher than Wada test.
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Full text: 1 Database: WPRIM Language: Zh Journal: Chinese Journal of Neuromedicine Year: 2013 Document type: Article
Full text: 1 Database: WPRIM Language: Zh Journal: Chinese Journal of Neuromedicine Year: 2013 Document type: Article