Long-term plasticity of HVC-RA synapses in adult male zebra finches / 生理学报
Acta Physiologica Sinica
; (6): 586-592, 2013.
Article
in Zh
| WPRIM
| ID: wpr-297534
Responsible library:
WPRO
ABSTRACT
Long-term synaptic plasticity is considered as a key part of the neural mechanism of learning and memory. The production of learned vocalization of male zebra finches is closely related to high vocal center (HVC)-robust nucleus of the arcopallium (RA) pathway. However, the long-term plasticity of HVC-RA synapses is unclear. This study investigated the long-term plasticity of HVC-RA synapses in adult male zebra finches through in vivo field potential recording. The results showed that physiologic stimulation, i.e., δ rhythmic stimulation and low frequency stimulation could not effectively induce long-term synaptic plasticity. The former leaded to no change of the amplitudes of evoked population spikes, and the latter induced short-term depression (STD) of the amplitudes of the second evoked population spikes caused by paired pulses. But high frequency stimulation induced long-term depression (LTD) of the amplitudes of evoked population spikes to show out long-term synaptic plasticity. These results suggest that LTD represents the long-term plasticity of HVC-RA synapses in adult male zebra finches, which may be a key part of the neural mechanism of vocal learning and memory and can explain the plasticity of adult song to some degree.
Full text:
1
Database:
WPRIM
Main subject:
Physiology
/
Synapses
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Finches
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Evoked Potentials, Auditory
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High Vocal Center
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Learning
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Neuronal Plasticity
Limits:
Animals
Language:
Zh
Journal:
Acta Physiologica Sinica
Year:
2013
Document type:
Article