The correlation between neck lymphy node metastasis and matrixmetalloproteinase-2 expression at the invasive tumor front of oral squamous cell carcinomas / 华西口腔医学杂志
West China Journal of Stomatology
; (6): 106-108, 2004.
Article
in Zh
| WPRIM
| ID: wpr-319046
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the correlation between neck lymph node metastasis and matrix metalloproteinase-2 expression at the invasive tumor front of oral squamous cell carcinomas(OSCC).</p><p><b>METHODS</b>Immunohistochemistry LsAB technique was used to observe the expression of MMP-2 at the invasive tumor front and center of OSCC, and the correlation between the expression of MMP-2 in OSCC and neck lymph node metastasis were respectively analyzed by statistics.</p><p><b>RESULTS</b>The results demonstrated that MMP-2 existed in all 71 cases, which the expression of MMP-2 at the OSCC front was more significant than that of MMP-2 at the OSCC center (P < 0.01), and related to neck lymph node metastasis (P < 0.05).</p><p><b>CONCLUSION</b>The expression of MMP-2 at the OSCC front could be considered as an index of judging the present of neck lymph node metastasis of OSCC.</p>
Full text:
1
Database:
WPRIM
Main subject:
Pathology
/
Mouth Neoplasms
/
Immunohistochemistry
/
Carcinoma, Squamous Cell
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Matrix Metalloproteinase 2
/
Lymph Nodes
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Lymphatic Metastasis
/
Neoplasm Invasiveness
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Zh
Journal:
West China Journal of Stomatology
Year:
2004
Document type:
Article