Relationship between heart-type fatty acid-binding protein and cardiovascular events after thoracic surgery in aged patients / 中国医师杂志
Journal of Chinese Physician
; (12): 536-538,543, 2016.
Article
in Zh
| WPRIM
| ID: wpr-604141
Responsible library:
WPRO
ABSTRACT
Objective To explore the predictive value of heart-type fatty acid-binding protein (HFABP) in predicting the cardiovascular events after none-cardiac thoracic surgery in aged patients.Methods Sixty eight aged patients were admitted from February 2012 to August 2014 and accepted none-cardiac thoracic surgery.The patients'general information and the incidence of postoperational cardiovascular events were recorded.Serum H-FABP was measured.The receiver operating characteristic (ROC) curve was constructed and the predictive effect of serum H-FABP for prognosis was analyzed.Results Eighteen patients were suffered from postoperative cardiovascular events (PCE).The level of H-FABP after surgery in patients with PCE was higher than that with none-PCE (P < 0.05).The serum concentration of H-FABP after surgery and NT-proBNP before surgery was the independent risk factors for the elderly patients undergoing non-cardiac thoracic surgery.The area under ROC of H-FABP was 0.840 (95% CI0.716 ~0.964,P <0.01).The sensitivity and specificity of predicting postoperational cardiovascular event with serum concentration of H-FABP >5.26μg/L was 77.8% and 84.0% (OR 15.944,95% CI4.239 ~59.978,P <0.01).Conclusions The level of H-FABP after surgery is an independent risk factor for the occurrence of PCE for the elderly patients undergoing non-cardiac thoracic surgery.It can predict the risk of PCE after non-cardiac thoracic surgery in aged patients.
Full text:
1
Database:
WPRIM
Type of study:
Prognostic_studies
/
Risk_factors_studies
Language:
Zh
Journal:
Journal of Chinese Physician
Year:
2016
Document type:
Article