Influence of preoperative nicorandil application on coronary no-reflow in patients with acute anterior myocardial infarction / 心血管康复医学杂志
Chinese Journal of cardiovascular Rehabilitation Medicine
; (6): 160-163, 2018.
Article
in Zh
| WPRIM
| ID: wpr-699372
Responsible library:
WPRO
ABSTRACT
Objective:
To explore influence of preoperative nicorandil application on coronary no-reflow during emer-gency percutaneous coronary intervention(PCI)in patients with acute anterior myocardial infarction(AAMI).Methods:
A total of 116 AAMI patients were randomly and equally divided into routine treatment group and nic-orandil group(received nicorandil based on routine treatment).TIMI grade,incidence rate of no-reflow,ECG ST-segment elevation resolution(STR)and incidence rate of major adverse cardiovascular events(MACE)after PCI were compared between two groups.Results:
Compared with routine treatment group after PCI,there were signifi-cant rise in percentage of infarct related artery(IRA)TIMI grade 3(77.6% vs.91.4%)and STR on 2h after PCI[(0.15 ± 0.05)mm vs.(0.18 ± 0.05)mm],and significant reductions in incidence rates of no-reflow(13.8% vs. 3.4%)and MACE(17.2% vs.5.2%)in nicorandil group after PCI,P<0.05 or <0.01.Conclusion:
Preoperative nicorandil application can reduce incidence rate of no-reflow after PCI,improve myocardial perfusion and reduce in-cidence rate of major adverse cardiovascular events.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of cardiovascular Rehabilitation Medicine
Year:
2018
Document type:
Article